Distinct functions of neuromedin u and neuromedin s in orange-spotted grouper
نویسندگان
چکیده
منابع مشابه
Comparison of feeding suppression by the anorexigenic hormones neuromedin U and neuromedin S in rats.
We compared the central mechanisms of feeding suppression by the anorexigenic hormones neuromedin U (NMU) and neuromedin S (NMS) in rats. I.c.v. injection of either NMU or NMS dose dependently decreased 3-h food intake during the first quarter of a dark period. Pretreatment involving i.c.v. injection of a specific anti-NMS IgG blocked the suppression of food intake induced by i.c.v.- and i.p.-i...
متن کاملHypothalamic actions of neuromedin U.
The central nervous system and gut peptide neuromedin U (NMU) inhibits feeding after intracerebroventricular injection. This study explored the hypothalamic actions of NMU on feeding and the hypothalamo-pituitary-adrenal axis. Intraparaventricular nucleus (intra-PVN) NMU dose-dependently inhibited food intake, with a minimum effective dose of 0.1 nmol and a robust effect at 0.3 nmol. Feeding in...
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This research was carried out to identify the different layers and cells of orange spotted grouper brain for further toxicological experiments and defects brought by xenobiotics during exposure periods.The anatomy and histology of the brain of orange spotted grouper was illustrated and compared to mammals and other fishes. The preserved structures of teleosts brain species were different as com...
متن کاملOvarian regulation of neuromedin U and its local actions in the ovary, mediated through neuromedin U receptor 2.
Neuromedin U (NMU) was originally identified as an anorexigenic peptide that modulates appetite as well as energy homeostasis through the brain-gut axis. Although growing evidence has linked NMU activity with the development of female reproductive organs, no direct expression of and function for NMU in these organs has been pinpointed. Using a superovulated rat model, we found that NMU is direc...
متن کاملEffects of sex steroid hormones on neuromedin S and neuromedin U2 receptor expression following experimental traumatic brain injury
Objective(s): Neuroprotective effects of female gonadal steroids are mediated through several pathways involving multiple peptides and receptors after traumatic brain injury (TBI). Two of these peptides are including the regulatory peptides neuromedin U (NMU) and neuromedin S (NMS), and their common receptor neuromedin U2 receptor (NMUR2). This study investigates the effects of physiological do...
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ژورنال
عنوان ژورنال: Journal of Molecular Endocrinology
سال: 2015
ISSN: 0952-5041,1479-6813
DOI: 10.1530/jme-15-0018